Rhodium Catalyzed Hydrogenation of Quinolines and Isoquinolines under Water-Gas Shift Conditions
نویسندگان
چکیده
منابع مشابه
Quinolines and isoquinolines
We move from benzo-fused pyrroles to benzo-fused pyridines and meet quinoline and isoquinoline. Isoquinolines will feature as benzylisoquinoline alkaloids in Chapter 51 and their synthesis will mostly be discussed there. In this section we shall concentrate on the quinolines. Quinoline forms part of the structure of quinine, the malaria remedy found in cinchona bark and known since the time of ...
متن کاملLigand effect on the rhodium porphyrin catalyzed hydrogenation of [2.2]paracyclophane with water: key bimetallic hydrogenation.
Rhodium porphyrin catalyzed hydrogenation of the aliphatic carbon-carbon σ-bond of [2.2]paracyclophane with water has been examined with a variety of tetraarylporphyrins and axial ligands. Mechanistic investigations show that RhIII(ttp)H, which can be derived from the reaction of [RhII(ttp)]2 with water without a sacrificial reductant, plays an important role in promoting bimetallic reductive e...
متن کاملEnantioselective iridium-catalyzed hydrogenation of 3,4-disubstituted isoquinolines.
The past decade has witnessed rapid progress in the field of asymmetric hydrogenation of aromatic compounds, a transformation, which is regarded as one of the most straightforward means for accessing enantiopure cyclic compounds. Extensive research has significantly expanded the substrate scope of this reaction, and substrates such as quinolines, quinoxalines, indoles, furans, pyrroles, pyridin...
متن کاملEnantioselective hydrogenation of isoquinolines.
Asymmetric hydrogenation of (hetero)arenes is one of the most straightforward ways to synthesize enantiomerically pure, saturated or partially saturated cyclic molecules. Recent progress has significantly expanded the substrate scope of this reaction. Whereas a number of highly efficient catalytic systems have been found for the asymmetric hydrogenation of quinolines, structurally related isoqu...
متن کاملPalladium-catalyzed asymmetric hydrogenation of 3-phthalimido substituted quinolines.
Homogeneous Pd-catalyzed asymmetric hydrogenation of 3-phthalimido substituted quinolines was successfully developed, providing facile access to chiral substituted tetrahydroquinolines bearing two contiguous stereogenic centers with up to 90% ee.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1989
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.62.2968